The popularity of cannabidiol or CBD has increased in recent years, especially after its legalization. However, is it as popular as other drugs? For this, you need to be aware of the pharmaceutical properties of CBD. Online dispensaries are selling CBD clinic products and recreational products in different forms. CBD oils are mainstream. You can also purchase a range of CBD-infused products such as edible gummies, sprays and more. Serious antioxidant and anti-inflammatory benefits also make CBD very useful in skin care products.
CBD is a non-psychoactive component that is billed to have certain health benefits. Although CBD is legalized, many patients still find it difficult to access CBD products. Mostly, this is because they are unable to separate myths from facts.
For medicinal use, a patient has to get a prescription from a doctor. It’s because CBD can interact with certain drugs. So, if a patient is getting treatment for some health condition, the patient should get a CBD prescription from the same doctor.
CBD is often sold as a food supplement. Not all manufacturers can claim that their CBD products are for medicinal use. Only certified manufacturers selling lab-tested products with proper warning labels can make such claims. Even medical professionals are in favor of CBD clinic products. This shows that the future of CBD clinic products in the medical arena is promising. The potential medical applications of CBD clinic products are open to discussion.
However, the prohibition of cannabis did not leave scope for research. Scientists never had sufficient data due to prohibitions. They were unable to do proper research due to data scarcity. As it is not illegal anymore, they can conduct randomized controlled trials to determine the efficacy of cannabis and its constituents.
Still, the evidence base is satisfactory and strong in some areas. Available clinical data highlights therapeutic benefits within chemotherapy-induced nausea and vomiting, chronic pain and multiple sclerosis spasticity. There is evidence suggesting that cannabinoids are very effective in stimulating appetite, sleep disorders, anxiety, Tourette’s syndrome, PTSD, dementia and glaucoma. CBD products are broadly used to treat the following three main types of ailments:
- Mental health issues
- Complex motor disorder
- Pain management
CBD clinic products can specifically treat medical conditions that have been widely overlooked in the past. This is what makes the CBD market so interesting.
In recent years, people with severe, long-term pain have started using CBD products for its health benefits.
The FDA has also approved the use of Epidiolex, a medically-licensed product for the treatment of certain types of seizure.
How Does CBD Work?
CBD clinic products interact with your endocannabinoid system. Your body naturally produces cannabinoids. The endocannabinoid system uses these cannabinoids to maintain homeostasis. The endocannabinoid system is one of the most important systems that maintain long term health. Endocannabinoids are remarkably similar to the phytocannabinoids found in cannabis. The following two receptors in human body are of significant importance when it comes to CBD:
CBD and THC bind to these two receptors. This creates neurosignals within the human brain and organs. CB1 receptors are found in the nervous system and brain. CB2 receptors are found in organs and the immune system. THC binds to CB1 receptors. Even when CBD does not bind well to any of these two receptors, CBD does have an indirect impact on these receptors. So far, the medical literature has reported more than 65 molecular targets for CBD.
A number of research and studies are in progress to examine this mechanism. The anti-anxiety property of CBD is due to 5-HT1A serotonin receptor activation. Benzodiazepines and other anti-anxiety medications target the GABA system. This shows that CBD uses a different neural pathway. In a study, anxiety patients on benzodiazepines were given medical cannabis therapy. Nearly 50% of the patients stopped using benzodiazepines after six months.
People with anxiety and PTSD commonly use CBD to self medicate. The use of CBD in this area is extensively tested. The results are very promising. As the body absorbs it easily, the effects of CBD are immediate as compared to other drugs. Some drugs can even take several days.
CBD binds to TRPV1 receptors. This affects pain perception. Drug developers primarily target this receptor to develop pain relief drugs. Keeping the opioid crisis in mind, we need non-addictive analgesics. The interaction between receptors and cannabinoids is very complex. As we understand these interactions more, we are going to see more significant discoveries in the near future.
What is the Future?
All studies so far have shown significant results. Still, there is a lot to do. We need to conduct large, long-term studies to answer all the unanswered questions. CBD is safe. There is no known significant side effect of CBD overdose.
CBD works well in the treatment of certain diseases. When taken after the doctor’s advice, it is least likely to cause any significant side effects.
All we need is more research.